Instituto de Óptica “Daza de Valdés”

Computational simulation of the optical performance of an EDOF intraocular lens in post-LASIK eyes


Madrid / December 1, 2023

Researchers from the Visual Optics and Biophotonics Laboratory of the IO-CSIC have carried out a computer simulation to evaluate the optical performance of an extended focus intraocular lens (EDOF) in eyes that have previously undergone a LASIK surgery. The results of this study offer new knowledge about the implantation of intraocular lenses in patients who have previously undergone refractive surgery.

People who have undergone LASIK surgery and require cataract surgery over the years have difficulties in calculating the best intraocular lens to implant due to the changes in the optical properties of the cornea produced by LASIK surgery. The cornea of a person undergoing LASIK surgery has a different shape than the cornea without previous operations and with some types of LASIK, in addition to correcting the refractive error, high-order aberrations are induced in the eye.
However, the results of this computational simulation suggest that the optics of EDOF intraocular lenses predominate over LASIK-induced aberrations and that this type of lens could be a viable option for these patients. With them, a greater depth of focus is achieved in exchange for a reduction in image quality.

Cataract surgery / Roman Zaiets
The study analyzed the optical performance of the AcrySof IQ Vivity model EDOF intraocular lenses in post-LASIK eyes. Using computer models of eyes that simulate the presence of an intraocular lens, the researchers evaluated image quality on the retina, depth of focus, and the appearance of halos.

The results obtained demonstrated that eyes simulated with EDOF IOL lenses presented a greater depth of focus compared to those eyes with monofocal IOL implants. Furthermore, it was observed that the presence of spherical aberrations and coma commonly induced in LASIK surgery had a minor impact on the performance of EDOF IOLs compared to monofocal IOLs.

Regarding the quality of the image on the retina, the parameter known as visual Strehl (VS) was used to quantify it. The results showed that eyes simulated with the EDOF-type lens had a lower VS score compared to eyes with monofocal IOLs, but this decrease was considered clinically insignificant.


In relation to the appearance of halos, it was observed that eyes with EDOF IOLs presented a reduction in the formation of halos compared to those with monofocal IOLs.

The team of researchers highlights the importance of continuing with additional studies to this one that incorporate patient-specific data and visual simulations in real patients who have had their vision corrected with LASIK surgery. This could provide greater support for the recommendations for the use of EDOF IOLs and contribute to further improving lens design and personalized lens selection.

This has been a research work in collaboration with the CSIC Institute of Optics, the 2EyesVision company and the Center for Visual Science at the University of Rochester in NY

IO-CSIC Communication

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